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The village Dedino is located on the territory of Municipality of Konche, on the ridge of the mountain Smrdeshnik, among Radovish field and the upper catchment area of Kriva Lakavica. Dedino is a hilly village located at an 689 meters altitude. The village is located on the mountain Smrdeshnik and is surrounded by a few hills. Across the village passes the regional road from Radovish to Municipality of Konche and separates the village in two parts: Gorno I Dolno Maalo. It is 10 km away from the city of Radovish.

According to tradition, it got its name after some grandfather and nephew who lived in this area. The name of the village Dedino is very old with oldest confirmation, written with the same shape Дѣдино from 1366, and according to the scientific interpretations it comes from the word grandfather or the personal Dedo, Dede. Having in mind that in older medieval times, even until present days for priests and religious dignitaries – bishops are called grandfather, because of the middle significant location it is possible that Dedino was a seating-place and dwelling for some grandfather-bishop and this is how it got its name Dedino – village, place.

The village Dedino is one of the oldest villages in Radovish and Lakavica of which testify written evidence from the 14th century. Namely, together with Rakitec, Konche and Lubnica, Dedino is mentioned in a written record from 1366, when the famous church “St. Stefan” was built in the village Konche. In the Turkish census “defteri” from the 16th century, i.e. in 1570, Dedino is encountered in 2 records, as a pure Christian Macedonian village that belonged within the framework of the district Strumica, part of the Kjustendil district. In the first record, it is written as an estate of some imperial servant, in which there were 14 abolished falconers and 21 more Christian Macedonian family that produced 45 loads of wheat, 53 loads of mixed crops, lentils, chickpeas, beans (from the kind merum), early-garden crops, grapes, fruits, un-fermented vine, hay, pigs were bred, and bees in baskets for which income of 5103 “akcinja” was made. In the second record, 21 Macedonian Christian families were listed, suitable with the first record, which produced 48 loads of wheat, 40 loads of mixed crops, grain, lentil, garden crops, beans, grapes and un-ermented vine, bred pigs and bees and made an income of 4585 “akcinja”. At the end of 19th century, the village had around 90 Macedonian houses, and its residents – dedinci dealt with agriculture, producing large wheat and animal husbandry, but their main occupation was production of quicklime. Dedinci made quicklime carried in Shtip, Radovish and Strumica. Earlier Dedino was an estate, but in that time was an independent village whose duties i.e. Spahilack was 370 lires, and there were even above 5.000 heads of cattle in the village.

At the end of 19th century, the village was a part of the Radovish district of the Ottoman Empire. Several historical events are related to the village, such as the making of the first bombs. The workshop for hand bombs in the village was opened at the end of 1895, but was closed in November, 1897. During the time of national-liberation movement in the village Dedino were staying the two Macedonian revolutionaries, Goce Delchev and Jane Sandanski. In 1897, in Dedino and Injevo the Radovish affair of MRO was taking place. On the 25th of August in Dedino, happened the murder of two collectors of taxes for tobacco, who according to their violence became unbearable for the people. With this murder happened the so-called “Dedinska afera”. The collectors of the tobacco tax performed a lot of robberies in the villages, because of which the local management of TMORO in Radovish brought the decision to stop them using force, and the village military in Dedino surrounded them and two of them were killed. The head of the group was wounded and managed to escape, after which gave a note to the military in Radovish which took over Dedino, and that’s how searches around the houses began where storage places with guns and ammunition were discovered, together with abuses and imprisonments when 116 peasants were imprisoned, while 123 were tortured. According to the data of the Bulgarian ethnographer Vasil K’nchov (“Macedonia. Ethnography and statistics”) from 1900, the village had 700 residents, all Macedonians.

Every year in the village, the holiday “St. Nikola” is celebrated on the 19th of December. There is a church “St. Nikola” built in the village, and it is located in the upper neighborhood of the north edge of the village. This church is the main village church located in the upper neighborhood, on the south edge of the village, and around it are the village graveyards. It was built in 1910 by the master Stoilov from the Maleshevija. It is not known when and by which archiere, it was enlighted. The icons from the 19th century are by an anonymous author.